96583-92-5Relevant academic research and scientific papers
Tetrachlorosilane and zinc chloride as a binary reagent for the preparation of 2-amino-6-chloropyridine-3,5-dicarbonitrile derivatives
Elmorsy, Saad S.,Sheta, Ahmed M.,Mashaly, Mohammad M. A.,Said, Samy B.
, p. 540 - 544 (2017/08/30)
[Figure not available: see fulltext.] A green one-pot method for efficient synthesis of 2-amino-6-chloropyridine-3,5-dicarbonitrile derivatives was developed, based on stirring of various aldehydes and malononitrile with tetrachlorosilane and zinc chloride under solvent-free conditions at room temperature for 3–10 h. The effects of zinc chloride and the reaction conditions were studied. Compounds were characterized by X-ray analysis and NMR spectroscopy.
Studies on the acetylation of 3,6-diamino-1H-pyrazolo[3,4-b]pyridine-5- carbonitrile derivatives
Chioua, Mourad,Soriano, Elena,Samadi, Abdelouahid,Marco-Contelles
experimental part, p. 861 - 872 (2010/08/22)
(Chemical Equation Presented) The acetylation reaction of the differently substituted 3,6-diamino-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile derivatives 1-6 is reported. The structure of the resulting acetamides has been investigated and confirmed by analy
Medicine comprising dicyanopyridine derivative
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Page 15, (2010/02/06)
Compounds having a high conductance-type of calcium-activated K channel opening effect and a smooth muscle relaxant effect for bladder based on the K-channel opening effect, which can be used in treating pollakiuria and urinary incontinence, are provided.
MEDICINE COMPRISING DICYANOPYRIDINE DERIVATIVE
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, (2008/06/13)
Compounds having a high conductance-type of calcium-activated K channel opening effect and a smooth muscle relaxant effect for bladder based on the K-channel opening effect, which can be used in treating pollakiuria and urinary incontinence, are provided. 3,5-Dicyanopyridine derivatives or their salts.
Synthesis of heterocyclic compounds containing three contiguous hydrogen bonding sites in all possible arrangements
Murray, Thomas J.,Zimmerman, Steven C.,Kolotuchin, Sergei V.
, p. 635 - 648 (2007/10/02)
The synthesis of compounds containing three contiguous hydrogen bond sites is reported. There are six ways of arranging three adjacent hydrogen bond donor (D) and acceptor (A) sites. General synthetic routes to heterocyclic compounds with each arrangement
A Synthesis of Heterocyclic Ring Systems. Pyridothienopyrrolizine and Pyridodithienodipyrrolizine
Peinador, Carlos,Veiga, M. Carmen,Vilar, Juan,Quintela, Jose M.
, p. 1299 - 1306 (2007/10/02)
A synthesis for two new polycyclic heterocyclic ring systems is reported.Cyclization of pyrrolidinocarboxamide derivatives of ethyl 3-(pyrrol-1-yl)thienopyridine-2-carboxylate (4) and ethyl 3,5-di(pyrrol-1-yl)dithienopyridine-2,6-dicarboxylate (11) afford iminium salts that were transformed into the new heteropolycyclic compounds (6) and (13), respectively.
