97579-37-8Relevant academic research and scientific papers
Total Synthesis of Leukotriene B44> and Homo-LTB4 from D-Mannitol
Merrer, Yves Le,Gravier-Pelletier, Christine,Micas-Languin, Dominique,Mestre, Francoise,Dureault, Annie,Depezay, Jean-Claude
, p. 2409 - 2416 (2007/10/02)
A convergent total synthesis of leukotriene B4 and its homo analogue has been carried out via enantiomerically pure α-hydroxy aldehydes, chiral key intermediates obtained from D-mannitol and connected at a four carbon atom interval by Wittig re
A Practical Preparation of α-Hydroxy and α,β-Dihydroxy Aldehydes, Useful Intermediates for the Synthesis of Arachidonic Acid Metabolites, starting with D-Glyceraldehyde Acetonide
Okamoto, Sentaro,Shimazaki, Toshiyuki,Kitano, Yasunori,Kobayashi, Yuichi,Sato, Fumie
, p. 1352 - 1355 (2007/10/02)
Optically active α-hydroxy and α,β-dihydroxy aldehydes, useful intermediates for synthesis of lipoxygenase metabolites of arachidonic acid, are synthesized highly diastereoselectively starting with readily available D-glyceraldehyde acetonide.
