FUT8 drives the proliferation and invasion of trophoblastic cells via IGF-1/IGF-1R signaling pathway

Add time:07/23/2019    Source:sciencedirect.com

IntroductionTrophoblast proliferation and invasion are essential for embryo implantation and placentation. Protein glycosylation is one of the most common and vital post-translational modifications, regulates protein physical and biochemical properties. FUT8 is the only known fucosyltransferase responsible for catalyzing α1,6-fucosylation in mammals, and α1,6-fucosylated glycoproteins are found to participate in various physiopathological processes. However, whether FUT8/α1,6-fucosylation modulates the functions of trophoblastic cells remains elusive.

We also recommend Trading Suppliers and Manufacturers of (1R)-3-Chloro-1-phenyl-propan-1-ol (cas 100306-33-0). Pls Click Website Link as below: cas 100306-33-0 suppliers

Prev:IGF-1R deficiency in human keratinocytes disrupts epidermal homeostasis and stem cell maintenance
Next:Dose-dependent induction of rat liver microsomal aryl hydrocarbon monooxygenase by benzo[k]fluoranthene)