Topical mitomycin-C reduced number of myofibroblasts in healing anoplasty wounds in Wistar rats
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Add time:07/19/2019 Source:sciencedirect.com
Background: Mitomycin-C (MMC) has been used for treating stricture. Topical MMC has been proven to inhibit fibroblasts proliferation and reduce the number of fibroblasts. Myofibroblasts are originally from fibroblasts. The scarring potential of myofibroblasts has been documented in many anatomical sites. The purpose of this study is to analyze the effect of topical MMC on myofibroblasts in healing anoplasty wounds in Wistar rats.
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