Vinyl Weinreb amides: a versatile alternative to vinyl ketone substrates for the Heck arylation
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Add time:07/23/2019 Source:sciencedirect.com
This paper describes the use of unsaturated Weinreb amides as excellent substrates for the Heck reaction. Subsequent derivatization of the products with organometallic reagents allowed access to a variety of substituted vinyl ketones that could not have been prepared directly via Heck reaction on unsaturated ketone precursors.
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