Four new amide derivatives of pyridinecarboxylic acids. Synthesis, structure and spectroscopic characterization

Add time:07/25/2019    Source:sciencedirect.com

This study treats about four new pyridine amide derivatives obtained by a simple and inexpensive method of synthesis which consisted in amide coupling of pyridine-2-carboxylic acid and pyridine-4-carboxylic acid chlorides and aromatic amines: methyl 2-amino-3-methylbenzoate (Ea), methyl 3-amino-2-methylbenzoate (Eb), methyl 3-amino-4-methylbenzoate (Ec). All products of synthesis: L1, L2, L3, L4 were analyzed in detail by FT-IR, 1H, 13C, COSY 2D, HSQC, HMBC NMR spectroscopy, elemental, TGA and X-ray analysis. The excitation and emission spectra for obtained amides were also registered. An exact examination of results confirmed receiving four amide compounds with higher potential ability to metal ion coordination than the substrates alone.

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