Reaction between nucleoside base residues and the phosphorylating agent derived from 1-hydroxybenzotriazole and 2-chloroprenyl phosphorodichloridate

Add time:07/22/2019    Source:sciencedirect.com

In the presence of 1-methylimidazole, 2-N-acyl guanine (as in 4a), thymine (as in 5a) and uracil (as in 5b) residues react readily with the phosphorylating agent derived from 2-chlorophenyl phosphorodichloridate (1a) and 1-hydroxybenzotriazole.

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