5′-deoxy-5′-difluoromethylthioadenosine, a potent enzyme-activated acylating agent of S-adenosyl-L-homocysteine hydrolase

Add time:07/22/2019    Source:sciencedirect.com

5′-Deoxy-5′-difluoromethylthioadenosine (DFMTA) caused potent time-dependent inactivation of S-adenosyl-L-homocysteine hydrolase. The mechanism of this inactivation was investigated.

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