Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease

Add time:07/24/2019    Source:sciencedirect.com

BackgroundEpidemiological, laboratory and clinical studies have established an association between elevated urate and high blood pressure (BP). However, the inference of causality remains controversial. A naturally occurring antioxidant, urate may also be neuroprotective, and urate-elevating treatment with its precursor inosine is currently under clinical development as a potential disease-modifying strategy for Parkinson's disease (PD).

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