Lipase mediated desymmetrization of 1,2-bis(hydroxymethyl)ferrocene in organic medium: Production of both enantiomers of 2-acetoxymethyl-1-hydroxymethylferrocene
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Add time:07/31/2019 Source:sciencedirect.com
Both enantiomers of 2-acetoxymethyl-1-hydroxymethylferrocene have been obtained via enantiotoposelective irreversible acylation in organic medium of 1,2-bis(hydroxymethyl)ferrocene using vinyl acetate as acyl donor and a lipase as catalyst.
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