5-(2-Carboxyethyl)-6-Hydroxy-7-Methoxybenzofuran, a Fungal Metabolite of xanthotoxin

Add time:07/26/2019    Source:sciencedirect.com

Tolerant strains of Gibberella pulicaris (anamorph: Fusarium sambucinum) metabolize the phytoalexin xanthotoxin to 5-(2-carboxyethyl)-6-hydroxy-7-methoxybenzofuran. This compound does not inhibit the growth of strains that are sensitive to xanthotoxin itself and all xanthotoxin-tolerant and xanthotoxin-sensitive strains tested were able to further degrade the metabolite. This is the first report of fungal detoxification of a furanocoumarin.

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