Nickel(II) chloride catalyzed one-pot synthesis of α-aminonitriles
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Add time:07/28/2019 Source:sciencedirect.com
A simple and efficient method has been developed for the synthesis of α-aminonitriles by simply mixing aldehydes, amines, and trimethylsilyl cyanides in the presence of a catalytic amount of NiCl2 at room temperature.
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