Indium trichloride catalyzed one-step synthesis of α-amino nitriles by a three-component condensation of carbonyl compounds, amines and potassium cyanide
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Add time:08/01/2019 Source:sciencedirect.com
A simple and general method has been developed for the synthesis of α-aminonitriles by a one-pot three-component condensation of aldehydes or ketones, amines and potassium cyanide in THF in presence of a catalytic amount of indium trichloride.
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