Preparation and ring-opening reactions of N-Diphenylphosphinyl aziridines

Add time:07/27/2019    Source:sciencedirect.com

Monochiral N-Diphenyphosphinyl aziridines (‘N-Dpp aziridines’) may efficiently be prepared from monochiral 2-aminoalcohols. Such aziridines undergo ring-opening reaction with a variety of nucleophiles in good yield. Dephosphinylation is accomplished under mild conditions.

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