A novel synthetic route to 2-amino-3-cyano-4-trifluoromethyl-6-substituted pyridines
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Add time:07/30/2019 Source:sciencedirect.com
2-Amino-3-cyano-4-trifluoromethyl-6-substituted pyridines have been obtained from 3-cyano-4-trifluoromethyl-6-substituted-2(1H)pyridones via an interesting rearrangement of 2-O-acetamido-3-cyano-4-trifluoromethyl-6-sub-stituted pyridine intermediates.
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