The synthesis of 12-fluoro-7-methyl- and 7-fluoro-benz[a]anthracene

Add time:07/29/2019    Source:sciencedirect.com

In order to study the influence of fluorine substitution at the meso-position of benz[a]anthracene and at the 12-position of 7-methylbenz[a]anthracene on the carcinogenic properties of these hydrocarbons, the title compounds have been prepared by photocyclization of 1-(1-f1uoro-2-naphthyl)-2-(o-iodophenyl)ethylene and 1-(4-fluoro-1-methyl-2-naphthyl)-2-(o-iodophenyl)ethylene, respectively.

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