ethambutol hydrochloride (cas 134566-79-3)

Add time:07/31/2019    Source:sciencedirect.com

Publisher SummaryThis chapter discusses ethambutol hydrochloride. Ethambutol is a white, scentless, bitter tasting, thermostable crystalline powder. An infrared (IR) spectrum of ethambutol hydrochloride obtained on a KBr disc is discussed in the chapter. The IR spectra for both free base and hydrochloride salt indicate the absence of free-OH in the ethambutol molecular hydrogen bonding. The nuclear magnetic resonance (NMR) spectrum was obtained by preparing a 2 mg/ml solution of ethambutol free base in deutero chloroform containing tetramethylsilane as the internal reference. Chemical ionization mass spectra of ethambutol were obtained using a quadrupole mass spectrometer. This method is based on the formation of a complex of bromothymol blue and ethambutol, a complex whose yellow color may be quantitatively measured by means of spectrophotometer.

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