Enzymatic inactivation of SRS-CYS-GLY (cas 19246-18-5) (leukotriene D)
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Add time:08/07/2019 Source:sciencedirect.com
SummaryThe peptidases in rat basophilic leukemia cells, guinea pig lung, peritoneal eosinophils and limpet arylsulfatase preparation were shown to inactivate SRS-Cys-Gly but not SRS-GSH and SRS-Cys. The SRS-Cys-Gly inactivating peptidases were resolved from arylsulfatases in these cell systems. We have shown that arylsulfatases do not inactivate SRS-Cys-Gly and that peptidases are probably the enzymes primarily responsible for modulating SRS-Cys-Gly levels invivo.
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