Synthesis of (3S,4R)-(+)-hydroxymethyl-3-(trifluoromethyl)-4,5,5-trimethylcyclopentene — a trifluoromethyl analogue of necrodol (cas 104086-70-6)s

Add time:08/03/2019    Source:sciencedirect.com

New trifluoromethyl group containing enantiomerically pure monoterpene derivatives, methyl (1S,3R,4S)-(+)-4-(trifluoromethyl)-2,2,3-trimethylcyclopentanecarboxylate (6); methyl (3S,4R)-(+)-3-(trifluoromethyl)-4,5,5-trimethylcyclopentenecarboxylate (10) and (3S,4R)-(+)-hydroxymethyl-3-(trifluoromethyl)-4,5,5-trimethylcyclopentene (1), were prepared using camphoric anhydride as the starting material and sulphur tetrafluoride as the fluorinating agent. Compound 1 is a trifluoromethyl analogue of an unknown isomer of necrodols.

We also recommend Trading Suppliers and Manufacturers of necrodol (cas 104086-70-6). Pls Click Website Link as below: cas 104086-70-6 suppliers

Prev:High diastereoselectivity in Claisen rearrangement in a sterically congested cyclopentane system. Total synthesis of (±)-β-necrodol (cas 104086-70-6)
Next:A Synthesis of β-necrodol (cas 104086-70-6) via a palladium catalyzed reductive enyne cyclization)