Synthesis of α-trifluoromethyl-phenethylamines from α-trifluoromethyl β-aryl enamines and β-chloro-β-(trifluoromethyl)styrenes

Add time:08/01/2019    Source:sciencedirect.com

A novel synthetic approach towards α-trifluoromethyl-phenethylamines was elaborated by reduction of the electron deficient β-aryl-α-trifluoromethyl enamines and imines with sodium cyanoborohydride in the presence of trifluoroacetic acid. The starting imines were prepared by the reaction of primary amines with β-aryl-α-trifluoromethyl enamines or β-chloro-β-(trifluoromethyl)styrenes.

We also recommend Trading Suppliers and Manufacturers of β-Methoxy-3-(trifluoromethyl)phenethylamine (cas 15235-08-2). Pls Click Website Link as below: cas 15235-08-2 suppliers

Prev:Low temperature hydrogenation of 1- and 2-phenylethanols with noble metal catalysts in supercritical carbon dioxide
Next:Phenethylamine Inhibitors of Partially Purified Rat and Human Pancreatic Lipase)