Stereochemistry of C-4 demethylation during conversion of obtusifoliol (cas 16910-32-0) into poriferasterol by Ochromonas malhamensis
-
Add time:08/09/2019 Source:sciencedirect.com
obtusifoliol (cas 16910-32-0)-[2,2,4-3H3] was synthesised and incubated with the chrysophyte alga Ochromonas malhamensis which converted it into poriferasterol. A reaction sequence applied to poriferasterol showed that the tritium retained at C-4 occupied the 4α-position. This demonstrates that biological C-4 demethylation of a 4α-methylsterol precursor by O. malhamensis results in the axial 4β-hydrogen being inverted into the equatorial 4α-position of the 4-desmethyl sterol product.
We also recommend Trading Suppliers and Manufacturers of obtusifoliol (cas 16910-32-0). Pls Click Website Link as below: cas 16910-32-0 suppliers
Prev:obtusifoliol (cas 16910-32-0) 14α-Demethylase (CYP51) Antisense Arabidopsis Shows Slow Growth and Long Life
Next:The 14α-demethylation of obtusifoliol (cas 16910-32-0) by a cytochrome P-450 monooxygenase from higher plants microsomes) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Plant sterol biosynthesis: Novel potent and selective inhibitors of cytochrome P450-dependent obtusifoliol (cas 16910-32-0) 14α-methyl demethylase08/11/2019
- The 14α-demethylation of obtusifoliol (cas 16910-32-0) by a cytochrome P-450 monooxygenase from higher plants microsomes08/10/2019
- obtusifoliol (cas 16910-32-0) 14α-Demethylase (CYP51) Antisense Arabidopsis Shows Slow Growth and Long Life08/08/2019
- Plant sterol biosynthesis: 7-oxo-obtusifoliol (cas 16910-32-0) analogues as potential selective inhibitors of cytochrome P-450 dependent obtusifoliol (cas 16910-32-0) 14α-demethylase08/07/2019
- obtusifoliol (cas 16910-32-0) and related steroids from the whole herb of Euphorbia chamaesyce08/06/2019
- Molecular Identification and Expression Analysis of GhCYP51G1 Gene, a Homologue of obtusifoliol (cas 16910-32-0)-14Alpha-Demethylase Gene, from Upland Cotton08/05/2019
- obtusifoliol (cas 16910-32-0) related steroids from Euphorbia sogdiana with cell growth inhibitory activity and apoptotic effects on breast cancer cells (MCF-7 and MDA-MB231)08/04/2019