Lithiated bis(diethylamino)phosphine borane complex as useful nucleophilic phosphorus reagent

Add time:07/11/2019    Source:sciencedirect.com

The reaction of bis(diethylamino)chlorophosphine borane complex with lithium naphthalenide affords the lithiated derivative 3 which undergoes nucleophilic substitution with primary and secondary alkyl halides, allylic and benzylic bromides and aryl iodides or bromides in good yields. The substitution of the diethylamino group via intermediate dichloroorganophosphine derivatives furnishes polyfunctional phosphines.

We also recommend Trading Suppliers and Manufacturers of BIS(DIETHYLAMINO)CHLOROPHOSPHINE (cas 685-83-6). Pls Click Website Link as below: cas 685-83-6 suppliers

Prev:Novel antagonists of serotonin-4 receptors: Synthesis and biological evaluation of pyrrolothienopyrazines
Next:A new efficient procedure for asymmetric synthesis of α-aminophosphonic acids via addition of lithiated bis(diethylamino)phosphine borane complex to enantiopure sulfinimines)