Synthesis and pharmacological study of 1-acetyl/propyl-3-aryl-5-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-pyrazoline

Add time:08/09/2019    Source:sciencedirect.com

A series of 1-acetyl/propyl-3-aryl-5-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-2-pyrazolines were synthesized in one step by condensing suitably substituted propenones, hydrazine and acetic/propionic acid. The newly synthesized pyrazolines were characterized by analytical and spectral data. The new compounds were screened for analgesic and anti-inflammatory activity and most of them showed good activity comparable with that of standard drugs Pentazocin and Diclofinac sodium respectively.

We also recommend Trading Suppliers and Manufacturers of 1-(2-CHLORO-ACETYL)-3-CYCLOHEXYL-UREA (cas 16467-50-8). Pls Click Website Link as below: cas 16467-50-8 suppliers

Prev:Synthesis, crystal structures and theoretical calculations of new 1-[2-(5-chloro-2-benzoxazolinone-3-yl)acetyl]-3,5-diphenyl-4,5-dihydro-(1H)-pyrazoles
Next:Reactivity of the dinuclear platina-β-diketone [Pt2{(COMe)2H}2(μ-Cl)2] towards chelating ligands – Bridge cleavage versus formation of acetyl(chloro)platinum(II) complexes)