Combined treatment with MINODRONATE (cas 127657-42-5) and vitamin C increases bone mineral density and strength in vitamin C-deficient rats
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Add time:08/12/2019 Source:sciencedirect.com
ObjectivesReduced bone quality caused by vitamin C deficiency in older persons may lead to incidental fragility fractures during bisphosphonate treatment, although bisphosphonate increases bone mineral density (BMD). This study aimed to evaluate the effects of MINODRONATE (cas 127657-42-5) and ascorbic acid (Aa) on BMD, bone quality, and bone strength in Aa-deficient osteogenic disorder Shionogi (ODS) rats.
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