A practical preparation of enantiomerically pure (R)- and (S)-2-BROMOHEXADECANOIC ACID (cas 18263-25-7)s

Add time:08/11/2019    Source:sciencedirect.com

The efficient preparation of enantiomerically pure (R)- and (S)-2-bromohexadecanoic acids with e.e.>95% through resolution with the use of a recoverable chiral auxiliary is described. The procedure involves three reactions: Steglich esterification, DIBAL reduction, and Sharpless oxidation. The assessment of the enantiomeric purity is based on NMR analysis by using (1R,2R)-(+)-diphenylethane-1,2-diamine as a chiral solvating agent.

We also recommend Trading Suppliers and Manufacturers of 2-BROMOHEXADECANOIC ACID (cas 18263-25-7). Pls Click Website Link as below: cas 18263-25-7 suppliers

Prev:Modification of the surfaces of Wyoming montmorillonite by the cationic surfactants alkyl trimethyl, dialkyl dimethyl, and trialkyl methyl ammonium bromides
Next:ArticleSynthesis and configurational assignment of (R) and (S)-2-BROMOHEXADECANOIC ACID (cas 18263-25-7)s)