ArticleSynthesis and configurational assignment of (R) and (S)-2-BROMOHEXADECANOIC ACID (cas 18263-25-7)s

Add time:08/12/2019    Source:sciencedirect.com

Synthesis of both enantiomers of 2-bromohexadecanoic acid is described by diastereoselective bromination of esters (+)- and (−)-3 followed by removal of the chiral auxiliary. The absolute configuration of the acids is confirmed by an independent chemical synthesis from chiral pool precursors.

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