Solid-phase synthesis of α-substituted 3-bisarylthio N-Hydroxy propionamides as Specific MMP Inhibitors

Add time:08/12/2019    Source:sciencedirect.com

A novel series of potent and specific MMP-2,3,9,13 inhibitors has been obtained by modulation on solid phase by α and aryl substitutions on 3-arylthio-N-hydroxy-propionamides starting from itaconic acid.

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