TRIPHENYL BORATE (cas 1095-03-0) catalyzed synthesis of amides from carboxylic acids and amines
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Add time:08/12/2019 Source:sciencedirect.com
Herein we report TRIPHENYL BORATE (cas 1095-03-0) as a new catalyst for synthesis of amides by catalytic condensation of carboxylic acids and amines. Our protocol is applicable for synthesis of wide range of amides furnishing excellent yields up to 92%. In addition developed method requires low catalyst loading, short time, less amount of solvent, works under air atmosphere and notably no need of azeotropic reflux using special Dean Stark apparatus or molecular sieves.
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