General paperChanges in ovulatory and steroidogenic responses in mice after administration of the ribosome inactivating proteins momorcochin, luffaculin and luffins

Add time:08/18/2019    Source:sciencedirect.com

1.1. Immature mice were induced to ovulate by pregnant serum gonadotropin and human chorionic gonadotropin.2.2. The ribosome inactivating proteins luffaculin, luffin-a, luffin-b and momorcochin were administered i.p.3.3. It was found that all four ribosome inactivating proteins elicited a reduction in the circulating titer of estradiol-17β.4.4. Both luffaculin and momorcochin brought about an increase in the number of degenerated oocytes.5.5. Only momorcochin caused a decrease in the ovarian weight and the number of ovulated oocytes.

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