Synthesis of (αR, 6R or 6S)-N-(α-methylbenzyl)-6-difluoromethyl-4- hydroxy-4- (4-chlorophenyl) piperidines

Add time:08/15/2019    Source:sciencedirect.com

Diasteroeselective synthesis of (αR, 6R or 6S)-N-(α-methylbenzyl)-6-difluoromethyl-4-hydroxy-4-(4-chlorophenyl)piperidines, which were produced from the reaction of R, 6R)- or (αR, 6S)-N-(α-methylbenzyl)-6-difluoromethyl-4-piperidone and 4-chlorophenyllithium, is described.

We also recommend Trading Suppliers and Manufacturers of 4-Methylbenzyl chloride (cas 104-82-5). Pls Click Website Link as below: cas 104-82-5 suppliers

Prev:Oxidative debenzylation of 4-methoxy-α-methylbenzyl esters
Next:Para-selective chlorination of benzyl chloride to 4-Chlorobenzyl chloride (cas 104-83-6) over zeolite catalysts)