ArticleSynthesis of α-phenyl-1-(R)-(−)-piperidineacetic esters

Add time:08/13/2019    Source:sciencedirect.com

Several α-phenyl-1-(R)-(−)-piperidineacetic esters 3(a-e), were obtained in pure enantiomeric form by condensing (R)-(−)-α-phenylglycine esters 2(a-e) with 1,5-dibromopentane. Similarly, (R)-(−)-α-phenylglycine esters, 2(a-e), were prepared from (R)-(−)-α-phenylglycine1 with high yields.

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