Three-component condensation of 2,4-diaminothiazoles with aldehydes and Meldrum's acid: synthesis of 7-aryl(alkyl)-substituted 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones

Add time:07/12/2019    Source:sciencedirect.com

The new method of the synthesis of 6,7-dihydro-4H-thiazolo[4,5-b]pyridin-5-ones, based on decarboxylation of corresponding 2,4-diamino-5-thiazolecarboxylic acids has been elaborated; unstable derivatives of 2,4-diaminothiazole, generated in situ as a result of decarboxylation, react with aldehydes and Meldrum's acid forming target compounds.

We also recommend Trading Suppliers and Manufacturers of 4-Thiazolecarboxylic acid, 5-amino-2-methyl- (cas 36405-01-3). Pls Click Website Link as below: cas 36405-01-3 suppliers

Prev:Theoretical studies on racemization of levetiracetam: Structural movements, character of hydroxide ion and guidelines for efficient control
Next:Monopyrrolotetrathiafulvalene-based supramolecular organogels: Multi-stimuli responsiveness and formation of charge-transfer salt gels)