Synthesis and biological activity of (γ-arylpyridino)-dibenzoaza-14-crown-4 ethers

Add time:08/14/2019    Source:sciencedirect.com

Eight novel aza-14-crown-4 compounds incorporating γ-arylpyridine moiety and possessing high inhibitory activity towards cancer cell lines were synthesized in one step from 1,5-bis(2-acetylphenoxy)-3-oxapentane, aromatic aldehyde and ammonium acetate.

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