Research letterAbsence of promotion potential for calcium l-ascorbate, l-ascorbic dipalmitate, l-ascorbic stearate and erythorbic acid on rat urinary bladder carcinogenesis

Add time:08/21/2019    Source:sciencedirect.com

The effects of treatment with calcium l-ascorbate, l-ascorbic dipalmitate, l-ascorbic stearate and erythorbic acid on two-stage urinary bladder carcinogenesis in F344 rats after initiation with N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) were examined. Carcinogen was administered at a dose of 0.05% in drinking water for 4 weeks and thereafter the test chemicals were given as a 5% supplement in the diet for the following 32 weeks. No increase in the induction of preneoplastic lesions, papillomas or carcinomas was apparent and it was concluded that none of the test chemicals possess promoting activity for urinary bladder carcinogenesis.

We also recommend Trading Suppliers and Manufacturers of L-Ascorbic acid 6-stearate (cas 10605-09-1). Pls Click Website Link as below: cas 10605-09-1 suppliers

Prev:The interaction of l-ascorbic acid with the active center of myrosinase
Next:Carbendazim (cas 10605-21-7) residues in vegetables in China between 2014 and 2016 and a chronic Carbendazim (cas 10605-21-7) exposure risk assessment)