Synthesis of a new structural analogue of (+)-porothramycin

Add time:08/17/2019    Source:sciencedirect.com

A new phosphonate analogue of (+)-porothramycin has been synthesized from (S)-pyroglutaminol. Circular dichroism of diastereomeric intermediates 9 has been studied. The cytostatic activity of the new pyrrolo[2,1-c][1,4]benzodiazepine has been evaluated against human KB cells.

We also recommend Trading Suppliers and Manufacturers of porothramycin B (cas 110652-72-7). Pls Click Website Link as below: cas 110652-72-7 suppliers

Prev:Enantioselective synthesis of (+) porothramycin B (cas 110652-72-7) and its 9-Demethoxy analogue
Next:Synthesis of pyrazino[2,3-e][1,4]diazepin-5-one and pyrazino[2,3-e]pyrrolo[1,2-a][1,4]diazepin-5-one derivatives via the intramolecular aza-Wittig reaction)