Research articleHighly regioselective biotransformation of GINSENOSIDE RB2 (cas 11021-13-9) into compound Y and compound K by β-glycosidase purified from Armillaria mellea mycelia

Add time:08/18/2019    Source:sciencedirect.com

BackgroundThe biological activities of ginseng saponins (ginsenosides) are associated with type, number, and position of sugar moieties linked to aglycone skeletons. Deglycosylated minor ginsenosides are known to be more biologically active than major ginsenosides. Accordingly, the deglycosylation of major ginsenosides can provide the multibioactive effects of ginsenosides. The purpose of this study was to transform GINSENOSIDE RB2 (cas 11021-13-9), one of the protopanaxadiol-type major ginsenosides, into minor ginsenosides using β-glycosidase (BG-1) purified from Armillaria mellea mycelium.

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