Interaction of covalently closed circular PM-2 DNA and Hedamycin (cas 11048-97-8)
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Add time:08/24/2019 Source:sciencedirect.com
The interaction of hedamycin with covalently closed circular PM-2 DNA was examined. Hedamycin produced strand breakage detectable in alkaline sucrose gradients. Under neutral conditions hedamycin inhibited ethidium bromide binding and induced conformational changes in PM-2 DNA.
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