An efficient synthesis of quinolones using N-phenyl(triphenylphosphoranylidene)ethenimine

Add time:08/20/2019    Source:sciencedirect.com

The acylphosphoranes 5 formed in a highly selective and sequential manner from the reaction of N-substituted anthranilic acids 1 and N-phenyl(triphenylphosphoranylidene)ethenimine 2 undergo intramolecular Wittig cyclization on the imide carbonyl to afford the pyrrolo- and pyrido[1,2-a]quinolones 6 in moderate to good yields.

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