Synthesis of (S) 2-ethyl-2-methylpentanoic acid from the formate ester of (S) ethyl 2-formyl-3-hydroxy-2-methylpropionate

Add time:08/17/2019    Source:sciencedirect.com

The synthesis of (S) 2-ethyl-2-methylpentanoic acid 13 from the C-5 aldehydo ester 1, obtained through a baker's yeast transformation, via C-2 and C-1 chain elongations by means of olefin-forming reactions is reported.

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