Highly efficient and diastereoselective synthesis of 1,3-oxazolidines featuring a palladium-catalyzed cyclization reaction of 2-Butene-1,4-diol (cas 110-64-5) derivatives and imines
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Add time:08/29/2019 Source:sciencedirect.com
A palladium-catalyzed protocol for effective synthesis of 1,3-oxazolidines has been reported. This method is featured by the high diastereoselectivity (dr up to >98/2) and using the readily available 2-Butene-1,4-diol (cas 110-64-5) derivatives and imines as substrates.
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