Data ArticlePhysicochemical data of Oleic acid (cas 112-80-1)-poloxamer organogel for intravaginal voriconazole delivery

Add time:08/20/2019    Source:sciencedirect.com

Functional polymeric nanoparticles have attracted attention for different biomedical applications, including drug delivery. Poloxamers (PL), a synthetic copolymers of poly(ethyleneoxide)-b-poly(propylene oxide)-b-poly(ethylene oxide), that exhibit thermoreversible behavior in aqueous solutions. Physicochemical properties of Oleic Acid-Poloxamer (OA-PL) organogel for intravaginal controlled Voriconazole (VRC) delivery were assessed using three different oils (isopropyl myristate - IPM, isopropyl palmitate - IPP, and oleic acid – OA, in order to select the most suitable oil phase for increasing the solubility of the drug and its dispersion in the final aqueous phase. Organogel structural organization was assessed by VRC partition coefficient, differential scanning calorimetry (DSC), rheological analysis, and drug release assay. These data are complementary to the research article entitled “Sodium alginate in oil-poloxamer organogels for intravaginal drug delivery: influence on structural parameters, drug release mechanisms, cytotoxicity and in vitro antifungal activity” - Materials Science and Engineering: C, 2019. 99: p. 1350–1361.

We also recommend Trading Suppliers and Manufacturers of Oleic acid (cas 112-80-1). Pls Click Website Link as below: cas 112-80-1 suppliers

Prev:Research ArticleDeleterious impact of elaidic fatty acid on ABCA1-mediated cholesterol efflux from mouse and human macrophages
Next:Hydrodeoxygenation of Oleic acid (cas 112-80-1) and palmitic acid to hydrocarbon-like biofuel over unsupported Ni-Mo and Co-Mo sulfide catalysts)