ReviewFragrance material review on 2-Phenoxyethanol (cas 112-99-6)

Add time:08/24/2019    Source:sciencedirect.com

A toxicologic and dermatologic review of 2-phenoxyethanol when used as a fragrance ingredient is presented. 2-Phenoxyethanol is a member of the fragrance structural group Aryl Alkyl Alcohols and is a primary alcohol. The AAAs are a structurally diverse class of fragrance ingredients that includes primary, secondary, and tertiary alkyl alcohols covalently bonded to an aryl (Ar) group, which may be either a substituted or unsubstituted benzene ring. The common structural element for the AAA fragrance ingredients is an alcohol group –C–(R1)(R2)OH and generically the AAA fragrances can be represented as an Ar–C–(R1)(R2)OH or Ar_Alkyl–C–(R1)(R2)OH group. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for 2-phenoxyethanol were evaluated then summarized and includes physical properties, acute toxicity, skin irritation, mucous membrane (eye) irritation, skin sensitization, elicitation, phototoxicity, photoallergy, toxicokinetics, repeated dose, and reproductive toxicity data. A safety assessment of the entire Aryl Alkyl Alcohols will be published simultaneously with this document; please refer to Belsito et al. (2012) for an overall assessment of the safe use of this material and all Aryl Alkyl Alcohols in fragrances.Belsito, D., Bickers, D., Bruze, M., Calow, P., Dagli, M., Fryer, A.D., Greim, H., Hanifin, J.H., Miyachi, Y., Saurat, J.H., Sipes, I.G., 2012. A toxicologic and dermatologic assessment of aryl alkyl alcohols when used as fragrance ingredients.

We also recommend Trading Suppliers and Manufacturers of 2-Phenoxyethanol (cas 112-99-6). Pls Click Website Link as below: cas 112-99-6 suppliers

Prev:Polyethylene glycol 400 significantly enhances the stimulation of 2-Phenoxyethanol (cas 112-99-6) on Vibrio qinghaiensis sp.-Q67 bioluminescence
Next:η6-(2-Phenoxyethanol (cas 112-99-6)) ruthenium(II)-complexes of 2,2′-bipyridine and its derivatives: Solution speciation and kinetic behaviour)