Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

2-Phenoxyethanol

Related Products

Hot Products

Basic Information Post buying leads Suppliers
Name

2-Phenoxyethanol

EINECS 204-589-7
CAS No. 122-99-6 Density 1.102 g/cm3
Solubility Soluble in alcohol, ether and sodium hydroxide solution. Can dissolve oil, natural resin, alkyd, cellulose acetate, ethyecellulose, nitrocellulose and polyvinyl acetate. Miscible with glycerin, propylene glycol, ethanol, ethyl ether, benzene. Melting Point 11-13 °C
Formula C8H10O2 Boiling Point 245.199 °C at 760 mmHg
Molecular Weight 138.16 Flash Point 105.275 °C
Transport Information Appearance colorless or light yellow liquid
Safety 26 Risk Codes 22-36
Molecular Structure Molecular Structure of 122-99-6 (Ethanol, 2-phenoxy-) Hazard Symbols HarmfulXn,IrritantXi
Synonyms

Sepicide LD;b-Hydroxyethyl phenyl ether;b-Phenoxyethanol;b-Phenoxyethyl alcohol;(2-Hydroxyethoxy)benzene;1-Hydroxy-2-phenoxyethane;2-Hydroxyethyl phenyl ether;2-Phenoxyethyl alcohol;Arosol;Dalpad A;Dowanol EP;Dowanol EPh;Emeressence1160;Ethylene glycol monophenyl ether;Ethylene glycol phenyl ether;Euxyl PE90120;H 4644;Hisolve EPH;NSC 1864;Newpol EFP;PHE (alcohol);PHE-G;PHE-S;Phenova;Phenoxethol;Phenoxetol;Phenoxyethanol;Phenoxyethyl alcohol;Phenyl cellosolve;Plastilit DS 3431;Rokafenol F 1;

 

2-Phenoxyethanol Specification

2-Phenoxyethanol is an organic compound with the formula C8H10O2, and its systematic name is the same with the product name. With the CAS registry number 122-99-6, it is also named as 2-Hydroxyethyl phenyl ether. It belongs to the product categories of Benzhydrols, Benzyl & Special Alcohols; Ethylene Glycols & Monofunctional Ethylene Glycols; Monofunctional Ethylene Glycols. Its EINECS number is 204-589-7. In addition, the molecular weight is 138.16. Its classification codes are: (1)Anesthetics; (2)Anti-Infective Agents; (3)Anti-infective agents, local; (4)Central Nervous System Agents; (5)Central Nervous System Depressants; (6)Mutation data; (7)Skin / Eye Irritant. This chemical should be sealed and stored in a cool and dry place. It is used as a fixative for perfumes, an insect repellent, a topical antiseptic, a solvent for cellulose acetate, some dyes, inks, and resins, and it is also used in organic synthesis. 

Physical properties of 2-Phenoxyethanol are: (1)ACD/LogP: 1.247; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.25; (4)ACD/LogD (pH 7.4): 1.25; (5)ACD/BCF (pH 5.5): 5.22; (6)ACD/BCF (pH 7.4): 5.22; (7)ACD/KOC (pH 5.5): 113.65; (8)ACD/KOC (pH 7.4): 113.65; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 29.46 Å2; (13)Index of Refraction: 1.526; (14)Molar Refractivity: 39.099 cm3; (15)Molar Volume: 127.449 cm3; (16)Polarizability: 15.5×10-24cm3; (17)Surface Tension: 39.97 dyne/cm; (18)Density: 1.084 g/cm3; (19)Flash Point: 105.275 °C; (20)Enthalpy of Vaporization: 50.962 kJ/mol; (21)Boiling Point: 245.199 °C at 760 mmHg; (22)Vapour Pressure: 0.016 mmHg at 25°C.

Preparation: this chemical can be prepared by tert-butyl-dimethyl-(2-phenoxy-ethoxy)-silane at the temperature of 80 °C. This reaction will need reagent P(Me2CHNCH2CH2)3N and solvent dimethylsulfoxide with the reaction time of 36 hours. The yield is about 95%.

2-Phenoxyethanol can be prepared by tert-butyl-dimethyl-(2-phenoxy-ethoxy)-silane at the temperature of 80 °C

Uses of 2-Phenoxyethanol: it can be used to produce N-(2-phenoxyethoxy)phthalimide at the ambient temperature. It will need reagents diethyl azodicarboxylate, triphenylphosphine and solvent tetrahydrofuran with the reaction time of 16 hours. The yield is about 72%.

2-Phenoxyethanol can be used to produce N-(2-phenoxyethoxy)phthalimide at the ambient temperature

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful if swallowed. It is irritating to eyes. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: c1ccc(cc1)OCCO
(2)Std. InChI: InChI=1S/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2
(3)Std. InChIKey: QCDWFXQBSFUVSP-UHFFFAOYSA-N

The toxicity data is as follows:  

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 490mg/kg (490mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996.
mouse LD50 oral 933mg/kg (933mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996.
rabbit LD50 skin 5mL/kg (5mL/kg)   Union Carbide Data Sheet. Vol. 6/24/1958,
rat LD50 intraperitoneal 554mg/kg (554mg/kg) BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996.
rat LD50 oral 1260mg/kg (1260mg/kg) BEHAVIORAL: GENERAL ANESTHETIC

GASTROINTESTINAL: OTHER CHANGES

KIDNEY, URETER, AND BLADDER: OTHER CHANGES
Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
rat LD50 skin 14422mg/kg (14422mg/kg) LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Journal of the American College of Toxicology. Vol. 9, Pg. 259, 1990.

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields