The prophylactic use of POLYVINYLPYRIDINE-N-OXIDE (cas 9045-81-2) (PVNO) in baboons exposed to quartz dust
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Add time:07/13/2019 Source:sciencedirect.com
Twelve baboons were exposed to a quartz dust cloud. Four of these were also given polyvinylpyridine-N-oxide (PVNO) by aerosol and four received PVNO by aerosol and injection. A prophylactic effect was demonstrated during the course of treatment, but when treatment stopped the silicosis progressed to the same degree of severity as in the untreated animals.
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