Synthesis of cis,cis,cis-1-alkylidene-2,3,4,5-tetrakis(diphenylphosphinomethyl)cyclopentanes

Add time:08/26/2019    Source:sciencedirect.com

A new strategy to prepare tetradentate or pentadentate diphenylphosphine ligands has been explored from Diels–Alder adducts of fulvenes and maleic anhydride. A tetradentate phosphine ligand, bearing a side chain allowing the formation of a bond with polystyrene resin, has been prepared in seven steps from cyclopentadiene. The cis,cis,cis-1-cyclohexylidene-2,3,4,5-tetrakis(diphenylphosphinomethyl)cyclopentane (Cyclo-Tedicyp) in combination with [PdCl(C3H5)]2 led to an efficient catalyst for the Heck, Suzuki and Sonogashira coupling reactions.

We also recommend Trading Suppliers and Manufacturers of 3-(hydroxymethyl)cyclopentane (cas 113681-11-1). Pls Click Website Link as below: cas 113681-11-1 suppliers

Prev:Original articleSynthesis and biological evaluation of cyclopentane-linked alkyl phosphocholines as potential anticancer agents that act by inhibiting Akt phosphorylation
Next:Synthesis, reactions and stereochemistry of 3-hydroxymethyl-2,3-dihydro-4H-1,3-benzoxazin-4-one and some perhydrogenated derivatives☆)