Synthesis and reactivity of 6-(fluoromethyl)indole and 6-(difluoromethyl)indole
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Add time:08/21/2019 Source:sciencedirect.com
The N-1 BOC protected precursors of 6-(fluoromethyl)indole and 6-(difluoromethyl)indole were prepared and deprotected via flash vacuum thermolysis. The stability of these newly prepared, unprotected indole derivatives has been characterized and compared to that of a previously known compound, 6-(trifluoromethyl)indole.
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