Synthesis of new trifluoromethylated indole derivatives
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Add time:08/25/2019 Source:sciencedirect.com
New indole trifluoromethyl derivatives have been synthesized using the reaction of indole derivatives with different 2,2,2-trifluoro-N-arylacetimidoyl chlorides in the presence of NaH as a base in acetonitrile at room temperature under an N2 atmosphere. The FT-IR, 19F NMR, 1H NMR, 13C NMR, COSY and HMBC spectra and elemental analysis confirm the structures of the products.
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