Biosynthesis of tolytoxin (cas 127999-44-4). Origin of the carbons and heteroatoms

Add time:08/21/2019    Source:sciencedirect.com

Preliminary studies on the biosynthesis of tolytoxin (1) in the terrestrial blue-green alga Scytonema mirabile BY-8-1 are reported. Incorporation experiments with [1,2-13C] acetate, [1-13C,18O]acetate, [1,2-13C]glycine, [2-13C,15N]glycine and [methyl- 13C]methionine indicate that the carbon chain of tolytoxin is a polyketide assembled from a glycine starter unit and 15 acetate units. The one-carbon branches on the polyketide chain originate from the tetrahydrofolate C1 pool.

We also recommend Trading Suppliers and Manufacturers of tolytoxin (cas 127999-44-4). Pls Click Website Link as below: cas 127999-44-4 suppliers

Prev:Iminoheptitols as glycosidase inhibitors: Synthesis of α-homomannojirimycin (cas 127995-29-3), 6-epi-α-homomannojirimycin (cas 127995-29-3) and of a highly substituted pipecolic acid
Next:Modification of styrene-isoprene block copolymers—5. Grafting)