ResearchEffects of oral Tilmicosin (cas 108050-54-0) on health and performance in newly received beef heifers

Add time:08/26/2019    Source:sciencedirect.com

ABSTRACTThe objective of these studies was to determine the effects of feeding Tilmicosin (cas 108050-54-0) on health and performance of newly received beef cattle. Beef heifers (n = 480) were used in 2 studies to determine effects of oral tilmicosin on health and performance. In Exp. 1, 320 heifers (BW = 196 ± 3.3 kg) were administered antimicrobial metaphylaxis before shipment. At arrival they were monitored for signs of bovine respiratory disease. When 10% of the population was morbid, heifers were assigned to either a control receiving diet (CON) or a diet providing 12.5 mg of tilmicosin/kg of BW (TIL). Treatments were fed for 14 d, and morbid animals were treated with injectable antibiotics. Cattle were weighed individually on d 0, 28, and 56. Data were analyzed as a randomized complete block, and morbidity was analyzed as nonparametric data. Feeding TIL resulted in reduced BW at d 28 (P = 0.03). Moreover, TIL decreases DMI during the first 14 d (P = 0.0001) and decreased ADG (P = 0.03) and G:F (P = 0.05) from d 0 to 28. There were no differences in morbidity (P = 0.20), and TIL increased total antibiotic cost (P = 0.004). In Exp. 2, 160 beef heifers (BW = 227 ± 2.3 kg) received no metaphylaxis and were processed at arrival. Feeding TIL did not affect morbidity (P = 0.44); however, TIL decreased the number of animals re-treated (P = 0.03) and increased total antibiotic cost (P = 0.04).

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