Cu-mediated C2-dehydrogenative homocoupling of indoles via C–H activation assisted by a removable N-pyrimidyl group
-
Add time:08/27/2019 Source:sciencedirect.com
A Cu-mediated regioselective, dehydrogenative homocoupling of indoles was developed using AgNO3 as the additive. The easily installed and removed N-pyrimidyl group exerted complete C2 regiocontrol via C–H activation. A series of indole substrates underwent cross-dehydrogenative-homocoupling. This work developed an effective approach for the synthesis of 2,2′-biindole core of a number of chemicals fundamentally important in material and pharmaceutical chemistry.
We also recommend Trading Suppliers and Manufacturers of 5-BENZYLOXY-6-METHYL INDOLE (cas 19500-00-6). Pls Click Website Link as below: cas 19500-00-6 suppliers
Prev:Chapter 8 - Indoles: As Multitarget Directed Ligands in Medicinal Chemistry
Next:Synthesis of a hexahydropyrrolo indole (HPI) compound library) - 【Back】【Close 】【Print】【Add to favorite 】
- Related Information
- Synthesis of a hexahydropyrrolo indole (HPI) compound library08/28/2019
- Chapter 8 - Indoles: As Multitarget Directed Ligands in Medicinal Chemistry08/26/2019
- TEMPO-catalyzed oxidative dimerization and cyanation of indoles for the synthesis of 2-(1H-indol-3-yl)-3-oxoindoline-2-carbonitriles08/25/2019
- Indole-TEMPO conjugates alleviate ischemia-reperfusion injury via attenuation of oxidative stress and preservation of mitochondrial function08/24/2019
- Research paperAlkyl indole-based cannabinoid type 2 receptor tools: Exploration of linker and fluorophore attachment08/23/2019
- Modification of Bischler-Möhlau indole derivatives through palladium catalyzed Suzuki reaction as effective cholinesterase inhibitors, their kinetic and molecular docking studies08/22/2019
- Review articleAn insight into the medicinal perspective of synthetic analogs of indole: A review08/21/2019
